Why are generic pills cheaper than the brand name ones?
The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability.
Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs.
First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions.
Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug.
Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.
Antibiotics / Generic Bactrim
Package
Price
Per Pill
Order
480mg x 90 pills
$10.00
US $ 0.11
480mg x 180 pills
$10.00
US $ 0.06
480mg x 360 pills
$10.00
US $ 0.03
Package
Price
Per Pill
Order
960mg x 30 pills
$54.95
US $ 1.83
960mg x 60 pills
$94.95
US $ 1.58
960mg x 90 pills
$134.95
US $ 1.50
What is Cotrimoxazole?
Cotrimoxazole is an antibiotic that treats different types of bacterial infections. It fights bacteria in your body.
Cotrimoxazole is used to treat infections such as urinary tract infections, bronchitis, ear infections (otitis), traveler's diarrhea, and Pneumocystis carinii pneumonia.
Cotrimoxazole may also be used for purposes other than those listed in this medication guide.
What should I discuss with my doctor before taking Cotrimoxazole?
Before taking this medication, tell your doctor if you have
kidney or liver disease, or
a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency).
You may not be able to take Cotrimoxazole, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
Cotrimoxazole is in the FDA pregnancy category C. This means that it is not known whether sulfamethoxazole and trimethoprim will harm an unborn baby. Do not take the medication without first talking to your doctor if you are pregnant.
Cotrimoxazole passes into breast milk and may harm a nursing baby. Do not take it without first talking to your doctor if you are breast-feeding a baby.
Cotrimoxazole is not approved for use in children younger than 2 months of age.
How should I take sulfamethoxazole and trimethoprim?
Take this drug exactly as directed by your physician. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Take it with food or milk if it upsets your stomach.
You may crush the tablets and put them in water or a soft food like applesauce or pudding if you cannot swallow them whole.
Take all of the Cotrimoxazole that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infections is completely treated.
Store the tablets at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
If you have only missed one dose, you can take the rest of your scheduled doses for that day at evenly spaced intervals.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a sulfamethoxazole and trimethoprim overdose include nausea, vomiting, decreased appetite, diarrhea, headache, yellowing of the skin or eyes, decreased urine production, bloody urine, and coma.
What should I avoid while taking sulfamethoxazole and trimethoprim?
Avoid prolonged exposure to sunlight. Cotrimoxazole may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
What are the possible side effects of Cotrimoxazole?
Stop taking the drug and seek emergency medical attention if you experience any of the following serious side effects:
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
unusual bleeding or bruising; or
yellow skin or eyes.
Other, less serious side effects may be more likely to occur. Continue to take your medication and talk to your doctor if you experience
headache, fatigue, or dizziness;
nausea, vomiting, decreased appetite, or diarrhea;
weakness; or
increased sensitivity to the sun.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
some medicines used to treat blood pressure and/or heart failure (ACE inhibitors such as benazepril, enalapril, lisinopril, moexipril, quinapril, ramipril, and others)
spironolactone
sulfinpyrazone
triamterene
trimetrexate
valproic acid
warfarin
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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